Presidency University

My laboratory is currently working on the therapeutic application of plant natural products on the three most deadly diseases viz. neurological and psychological disorders, cancer and diabetes. We are primarily in search of natural products and templates with ameliorative principles against these life-threatening ailments either linked to genetics and/or lifestyle. In addition, we are engaged in interpreting the possible role of plant natural products against the cause, complications and side effects of the above-mentioned diseases such as cardiovascular diseases, hypertension, substance abuse, obesity etc. Of late, we have also started to decipher the intrinsic molecular mechanisms, signal transduction pathways etc. in relation to disease pathogenesis for proper elucidation of drug targets, druggability and bioavailability. Besides, our ongoing research interest also deals with the plant-based antivirals and plant-derived toxins.

Being a frequent visitor to the Himalayas, I always have a special affinity to the north east Himalaya and I have always tried to expand this inclination into a scientific endeavour through a truly interdisciplinary research approach. Our study involves many domains of science such as phytochemistry, chemotaxonomy, molecular biology, plant biotechnology, mathematical modelling, process optimization, ecology and biodiversity, stress physiology, network pharmacology, molecular docking and bioinformatics. We are actively engaged in medicinal plant and natural product research using chemotaxonomy and molecular biology to characterize promising germplasm, biotechnological tools for generating in vitro plant materials for elicitation of secondary metabolites, isolation, purification and characterization of plant natural products using HPLC, HPTLC, GC-MS, NMR etc., molecular characterization of endophytes associated with natural products, bioinformatics tools for deciphering the potential phytochemicals against pathogens and diseases, mathematical modelling and process optimization in extraction of valuable natural products and last but not the least the field inventorization, taxonomy and identification of medicinal plants and their diversity.

My teaching areas include Plant Biotechnology, Molecular Biology, Cell Biology, Genetics, Phycology, Bryology, Gymnology, Economic Botany, Plant Groups, Bioethics, Pharmacology and Embryology for the past 15 years at UG as well as at PG levels.

PhD, Presidency University, 2018
M. Sc Botany, University of Calcutta, First Class First (Gold medallist), 2004
B. Sc: Botany, Presidency College, 2002
CSIR-NET (Shortlisted for SPM fellowship for being among the top 20% of NET qualified candidates), 2004
SLET, 2004
GATE, 2005

Dr. Abhijit Dey had completed his BSc from the erstwhile Presidency College in 2002 and MSc from the University of Calcutta in 2004. He completed his PhD from Presidency University. He stood First Class First in MSc and was the Gold medallist as the university topper in his subject. He also won the prestigious Prof. H. L. Chakraborty memorial award presented by the Botanical Society of Bengal for the same. Subsequently he qualified NET (CSIR-JRF & LS), 2004, Ministry of HRD, Govt. of India; SLET, 2004, College Service Commission (CSC), West Bengal, India and GATE, IIT, Bombay, 2005. He was also shortlisted for Shyma Prasad Mukherjee Fellowship for being among the top 20% of the NET-qualified candidates in 2004 all over India. He ranked First in both PSC (Public Service Commission) and CSC (College Service Commission) College Lecturer recruitment panels, in the state of West Bengal, India for Botany in 2006. He was elected as the Fellow of the Linnean Society of London in 2018. He was also included among the world Ranking of Top 2% Scientists in 2021 database (Published: 19 October 2021) created by experts at Stanford University, USA in association with Elsevier BV and Plos Biology. He has been nominated (invited) for Full Membership into Sigma Xi in 2021.

World Ranking of Top 2% Scientists in 2021 database (Published: 19 October 2021) created by experts at Stanford University, USA in association with Elsevier BV and Plos Biology

Fellow of the Linnean Society of London (FLS) in 2018 (Formation in the year 1788; ex-fellows: Sir Charles Darwin, William Roxburgh, Arthur William Hill and others)

“Dr. P. D. Sethi Memorial Award 2015, 2017, 2020” for the Best Research Paper on “Application of TLC/ HPTLC in Pharma, Herbal and other Analysis” awarded by Anchrom Enterprises (I) Pvt. Ltd.

Awarded the “outstanding contribution in reviewing” by Biomedicine & Pharmacotherapy, Elsevier, in Nov. 2017

Associate Editor: BMC Complementary Medicine and Therapies (Springer Nature)

Editorial Board: Plos One; Frontiers in Pharmacology; Frontiers for Young Minds

Reviewer for journals:

Drug Discovery Today, Elsevier, Impact factor: 7.851 (1); Pharmacological Research, Elsevier, Impact factor: 7.658 (1); Frontiers in Cell and Developmental Biology: Impact factor 6.684 (1); Horticulture Research, Nature, Impact factor: 6.793 (1); Process Safety and Environmental Protection, Elsevier, Impact factor: 6.158 (1); Biomedicine & Pharmacotherapy, Elsevier, Impact Factor: 6.529 (4); Frontiers in Oncology, Impact factor: 6.244 (1); Frontiers in Pharmacology. Impact factor: 5.810 (6); Phytotherapy Research, Wiley, Impact Factor: 5.878 and 52 more journals.

Reviewer (Book series/Encyclopaedia)

1. Studies in Natural Products Chemistry (Bioactive Natural Products), (Book Series), Edited by Prof. Atta-ur Rahman ISBN: 13: 978-0-444-59603-1; Elsevier Science Publishers, Amsterdam

2. UNESCO-EOLSS entitled “Beneficial Health Effects of Lupeol Triterpene and Medicinal Properties.”

Post Graduate: Botany and Biological/Life Sciences 15+ YEARS; Under Graduate: Botany and Biological/Life Sciences 15+ YEARS (Honours and Pass)

Currently supervising 3 NET JRFs for PhD.

International Society of Ethnobiology, Bristol, UK
SILAE-Società Italo-Latinoamericana di Etnomedicina (Italo-Latinamerican Society of Ethnomedicine)
International Association of Academicians-IAASSE, USA
International Society of Intraoperative Radiation Therapy (ISIORT), Austria
International Society of Infectious Diseases (ISID), Brookline, MA

Selected publications

1. Qi X, Jha SK, Jha NK, Dewanjee S, Dey A, Deka R, Pritam P, Ramgopal K, Liu W, Hou K, 2022. Antioxidants in Brain Tumors: Current Therapeutic Significance and Future Prospects. Molecular Cancer, BMC. Impact Factor: 41.444

2. Das T, Anand, U, Pandey SK, Ashby Jr, Assaraf YG, Chen ZS, Dey A*, 2021. Therapeutic strategies to overcome taxane resistance in cancer. Drug Resistance Updates 55, 100754. Elsevier, Impact Factor: 22.841. https://doi.org/10.1016/j.drup.2021.100754

3. Anand U, Nandy S, Mundhra A, Das N, Pandey DK, Dey A*, 2020. A review on antimicrobial botanicals, phytochemicals and natural resistance modifying agents from Apocynaceae family: Possible therapeutic approaches against multidrug resistance in pathogenic microorganisms. Drug Resistance Updates 51, 100695. Elsevier, Impact Factor: 22.841. https://doi.org/10.1016/j.drup.2020.100695

4. Mukherjee AG, Wanjari UR, Das S, Murli R, Renu K, Dey A, Gopalakrishnan AV, 2022. The pathophysiological and immunological background of the monkeypox virus infection: An update. Journal of Medical Virology. Impact Factor: 20.693. Wiley.

5. Dey A*, Bhattacharya R, Mukherjee A, Pandey DK, 2017. Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions. Biotechnology Advances 35, 178-216. Elsevier. Impact Factor: 17.681. https://doi.org/10.1016/j.biotechadv.2016.12.005

{C}{C}{C}{C}{C}{C}6. {C}{C}{C}{C}{C}{C}Jha NK, Arfin S, Jha SK, Kar R, Dey A, Gundamaraju R, Ashraff GM, Gupta PK, Dhanasekaran S, Abomughaid MM, Das S, Singh SK, Dual K, Roychoudhury S, Kumar D, Ruokolainen J, Ojha S, Kesar KK, 2022. Re-establishing the comprehension of phytomedicine and nanomedicine in inflammation-mediated cancer signalling. Seminars in Cancer Biology. Elsevier. Impact Factor: 17.012. https://doi.org/10.1016/j.semcancer.2022.02.022

{C}{C}{C}{C}{C}{C}7. {C}{C}{C}{C}{C}{C}Bhattacharyya N, Anand U, Kumar R, Ghorai M, Aftab T, Jha NK, Rajapaksha AU, Bundschuh J, Bontempi E, Dey A*, 2022. Phytoremediation and sequestration of soil metals using the CRISPR/Cas9 technology to modify plants: a review. Environmental Chemistry Letters. Springer. Impact Factor: 13.615.

{C}{C}{C}{C}{C}{C}8. {C}{C}{C}{C}{C}{C}Bontempi E; Anand U; Adelodun B; Cabreros C; Kumar P; S. Suresh; Dey A; Ballesteros F, 2022. Impact of pharmaceuticals and personal care products (PPCPs) in different environmental compartments through wastewater treatment plants: A review. Environmental Chemistry Letters. Springer. Impact Factor: 13.615.

{C}{C}{C}{C}{C}{C}9. {C}{C}{C}{C}{C}{C}Anand U; Dey S; Federici S; Ducoli S; S. Suresh; Vethaak AD; Bontempi E; Dey A*, 2022. Microplastic degradation: A critical review of approaches and prospects using modern biotechnological methods. Environmental Chemistry Letters. Springer. Impact Factor: 13.615.

{C}{C}{C}{C}{C}{C}10. {C}{C}{C}{C}{C}{C}Dhar R, Mukherjee D, Mukerjee, N; Devi, A; Dey A*, Ghosh A, 2022. Exosome based diagnostic and therapeutic approach in breast cancer, a new answer for the Indian breast cancer-associated health crisis. International Journal of Surgery, Elsevier. Impact Factor: 13.4.

{C}{C}{C}{C}{C}{C}11. {C}{C}{C}{C}{C}{C}Das T, Mukerjee, N; Ghosh A, Lorenzo JM, Dhama K, Dey A*, 2022. Growing risk of aristolochic acid nephropathy in the era of COVID-19. International Journal of Surgery, Elsevier. Impact Factor: 13.4.

{C}{C}{C}{C}{C}{C}12. {C}{C}{C}{C}{C}{C}Tuyelee Das, Samapika Nandy, Arabinda Ghosh, Deepak Chandran, Anil K. Sharma, Kuldeep Dhama, Dey A*, 2022. Efficacy of Smallpox Approved Tecovirimat (Tpoxx) drug against Monkeypox - Current Update and Futuristic Prospects. International Journal of Surgery, Elsevier. Impact Factor: 13.4.

{C}{C}{C}{C}{C}{C}13. {C}{C}{C}{C}{C}{C}Sirwan Khalid Ahmed, Rabab Gad Abd El-Kader, Salar Omar Abdulqadir, Renas Mohammad Khdir, Nahed A. El-Shall, Deepak Chandran, Dey A, Talha Bin Emran, Kuldeep Dhama, 2022. Monkeypox Clinical Symptoms, Pathology and Advances in Management and Treatment Options - An Update. International Journal of Surgery, Elsevier. Impact Factor: 13.4.

{C}{C}{C}{C}{C}{C}14. {C}{C}{C}{C}{C}{C}Chakraborty P; Das S; Dey A, Chakraborty A, Bhattacharyya C, Kandimalla R; Mukherjee B, Gopalakrishnan AV, Singh SK, Kant S, Nand P, Jha NK, Jha SK, Dewanjee S, 2022. Quantum Dots: The Cutting-Edge Nanotheranostics in Brain Cancer Management. Journal of Controlled Release. Elsevier. Impact Factor: 11.467

{C}{C}{C}{C}{C}{C}15. {C}{C}{C}{C}{C}{C}Kumar M, Hasan M, Choyal P, Tomar M, Gupta OP, Sasi M, Changan S, Punia S, Singh S, Sampathrajan V, Dhumal S, Pandiselvam R, Sharma K, Satankar V, Waghmare R, Senapathy M, Sayed AAS, Radha, Dey A, Amarowicz R, Kennedy JF, 2022. Cottonseed feedstock as a source of plant-based protein and bioactive peptides: Evidence based on biofunctionalities and industrial applications. Food Hydrocolloids 131, 107776. Elsevier, Impact Factor: 11.504. https://doi.org/10.1016/j.foodhyd.2022.107776

{C}{C}{C}{C}{C}{C}16. {C}{C}{C}{C}{C}{C}Kumar M, Selvasekaran P, Kapoor S, Barbhaia MD, Lorenzod JM, Saurabh V, Potkule J, Changan S, Kelishi AE, Selim S, Sayed AAS, Radha, Singh S, Senapathy M, Pandiselvam R, Dey A, Dhumal S, Natta S, Amarowicz R, Kennedy JF, 2022. Moringa oleifera Lam. seed proteins: Extraction, preparation of protein hydrolysates, bioactivities, functional food properties, and industrial application. Food Hydrocolloids. Impact Factor: 11.504. Elsevier. https://doi.org/10.1016/j.foodhyd.2022.107791

{C}{C}{C}{C}{C}{C}17. {C}{C}{C}{C}{C}{C}Kumar R, Ivy N, Bhattacharya S, Dey A, Sharma P, 2022. Coupled effects of microplastics and heavy metals on plants: uptake, bioaccumulation, and environmental health perspectives. Science of the Total Environment 836, 155619. Elsevier, Impact Factor: 10.753. https://doi.org/10.1016/j.scitotenv.2022.155619

{C}{C}{C}{C}{C}{C}18. {C}{C}{C}{C}{C}{C}Anand U, Carpena M, Kowalska-Góralska M, Garcia-Perez P, Sunita K, Bontempi E, Dey A, Prieto MA, Pro?kówJ, Simal-Gandara J, 2022. Safer plant-based nanoparticles for combating antibiotic resistance in bacteria: A comprehensive review on its potential applications, recent advances, and future perspective. Accepted. Science of the Total Environment 821, 153472, Elsevier, Impact Factor: 10.753. https://doi.org/10.1016/j.scitotenv.2022.153472

{C}{C}{C}{C}{C}{C}19. {C}{C}{C}{C}{C}{C}Anand U, Vaishnav A, Sharma SK, Sahu J, Ahmad S, Sunita K, Suresh S, Dey A, Bontempi E, Singh AK, Pro?ków J, Shukla ak, 2022. Current advances and research prospects for agricultural and industrial uses of microbial strains available in world collections. Science of the Total Environment. Elsevier, Impact Factor: 10.753. https://doi.org/10.1016/j.scitotenv.2022.153472

{C}{C}{C}{C}{C}{C}20. {C}{C}{C}{C}{C}{C}Dey A*, 2021. CRISPR/Cas genome editing to optimize pharmacologically active plant natural products. Pharmacological Research 164, 105359. Elsevier, Impact Factor: 10.334. https://doi.org/10.1016/j.phrs.2020.105359

{C}{C}{C}{C}{C}{C}21. {C}{C}{C}{C}{C}{C}Kumar V, Ameen F, Islam MA, Agrawal S, Motghare A, Dey A, Shah MP, Américo-Pinheiro JHP, Singh S, Ramamurthy PC, 2022. Evaluation of cytotoxicity and genotoxicity effects of refractory pollutants of untreated and biomethanated distillery effluent using Allium cepa. Environmental Pollution 300, 118975. Elsevier, Impact Factor: 9.988. https://doi.org/10.1016/j.envpol.2022.118975

{C}{C}{C}{C}{C}{C}22. {C}{C}{C}{C}{C}{C}Bhattacharjee R; Jana A; Bhattacharjee A; Mitra S; Kar S; Dey A; Panda PK; Singh SK; Suar M; Varma RS, Verma SK, 2022. Synergy of Nanocarriers with CRISPR-Cas9 in an Emerging Technology Platform for Biomedical Appliances: Current Insights and Perspectives. Materials & Design. Impact Factor: 9.417

{C}{C}{C}{C}{C}{C}23. {C}{C}{C}{C}{C}{C}Kumar M, Kapoor S, Dhumal S, Tkaczewska J, Changan S, Saurabh V, Mekhemar M, Rais N, Satankar V, Pandiselvam R, Sayed AA, Senapathy M, Anitha T, Singh S, Tomar M, Dey A, Zengin G, Amarowicz R, Bhuyan DJ 2022. Guava (Psidium guajava L.) seed: A low-v olume, high-value byproduct for human health and the food industry. Food Chemistry, 386, 132694. Impact Factor: 9.231. https://doi.org/10.1016/j.foodchem.2022.132694

{C}{C}{C}{C}{C}{C}24. {C}{C}{C}{C}{C}{C}Kumar M, Yadav R; Mhatre P; Sonawane S; Sharma S; Gat Y; Chandran D; Radha; Hasan M; Dey A; Sarkar T; Banwo K; Alao M; Balakrishnan J; Lorenzo J, Waghmare RB, 2022. Application of ultrasonication as pre-treatment for freeze drying: An innovative approach for the retention of nutraceutical quality in foods. Food Chemistry, Impact Factor: 9.231.

{C}{C}{C}{C}{C}{C}25. {C}{C}{C}{C}{C}{C}Bhattacharyya N, Pandey V, Bhattacharyya M, Dey A*, 2021. Regulatory role of long non coding RNAs (lncRNAs) in neurological disorders: From novel biomarkers to promising therapeutic strategies. Asian Journal of Pharmaceutical Sciences 16, 533-550. Impact Factor: 9.273. https://doi.org/10.1016/j.ajps.2021.02.006

{C}{C}{C}{C}{C}{C}26. {C}{C}{C}{C}{C}{C}Jangra A; Verma M; Kumar D; Chandrika; Rachamalla M; Dey A; Dua K; Jha SK; Ojha S; Kumar D; Jha NK; Athanasios A, 2022. Targeting Endoplasmic Reticulum Stress using Natural Products in Neurological Disorders. Neuroscience and Biobehavioral Reviews. Impact Factor: 9.052.

{C}{C}{C}{C}{C}{C}27. {C}{C}{C}{C}{C}{C}Mani S; Jindal D; Chopra H; Jha SK; Singh SK; Ashraf GM; Dey A; Dewanjee S, Singh KK; Ojha S; Singh I; Jha NK, Gautam R, 2022. ROCK2 Inhibition: A Futuristic Approach for Management of Alzheimers’ disease. Neuroscience and Biobehavioral Reviews. Impact Factor: 9.052.

{C}{C}{C}{C}{C}{C}28. {C}{C}{C}{C}{C}{C}Agrawal K, Chakraborty P, Dewanjee S, Arfin S; Das SS; Dey A; Moustafa M, Mishra PC, Jafari SM, Jha SK, Jha NK; Kumar D, 2022. Neuropharmacological Interventions of Quercetin and Its derivatives in Neurological and Psychological Disorders. Neuroscience and Biobehavioral Reviews. Impact Factor: 9.052.

{C}{C}{C}{C}{C}{C}29. {C}{C}{C}{C}{C}{C}Mukherjee AG, Wanjari UR, Bradu P, Patil M, Biswas A, Murali R, Renu K, Dey A, Vellingiri B, Raja G, Iyer M, Gopalakrishnan AV, 2022. Elimination of microplastics from the aquatic milieu: A dream to achieve. Chemosphere, 303, 135232. Elsevier, Impact Factor: 8.943. https://doi.org/10.1016/j.chemosphere.2022.135232

{C}{C}{C}{C}{C}{C}30. {C}{C}{C}{C}{C}{C}de la Lastra JMP, Anand U, González-Acosta S, R López M, Dey A, Bontempi E, De La Nuez AJM, 2022. Antimicrobial resistance in the COVID-19 landscape: Is there an opportunity for anti-infective antibodies and antimicrobial peptides? Frontiers in Immunology 13, 921483. Impact Factor: 8.786. https://doi.org/10.3389/fimmu.2022.921483

{C}{C}{C}{C}{C}{C}31. {C}{C}{C}{C}{C}{C}Anand U, Li X, Sunita K, Lokhandwala S, Gautam P, Suresh S, Sarma H, Vellingiri B, Dey A, Bontempi E, Jiang, G, 2022. SARS-CoV-2 and other pathogens in municipal wastewater, landfill leachate, and solid waste: a review about virus surveillance, infectivity, and inactivation. Environmental Research 203, 111839. Impact Factor: 8.431. https://doi.org/10.1016/j.envres.2021.111839

{C}{C}{C}{C}{C}{C}32. {C}{C}{C}{C}{C}{C}Dey, S; Anand U; Kumar, V; Kumar, S; Ghorai, M; Ghosh, A; Kant, N; S. Suresh; Bhattacharya S; Bontempi, E; Bhat SA, Dey A*, 2002. Microbial strategies for degradation of microplastics generated from COVID-19 healthcare waste. Environmental Research, Impact Factor: 8.431.

Abhijit Dey

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Abhijit Dey Associate Professor