Amlan Ghosh

Professor

B.Sc (Zoology HONS),1999

M.Sc (Zoology), 2001

Ph.D. (Molecular Biology of head and Neck Squamous Cell Carcinoma), 2010

My Ph.D. Work was at Chittaranjan National Cancer Institute, Kolkata from 2003-2009.  

During my predoctoral research, I have learnt several techniques like DNA/RNA isolation, Southern/Northern/Western blot, PCR/Real-Time PCR, Sanger DNA sequencing, Immunohistochemistry etc. and also gained some experience to handle research grants.

After my Ph.D. work, I have successfully completed a minor research project funded by UGC and two major research projects ants funded by WBDST and WDBT (Collaborative Project).

At present I have one ongoing research project funded by DSTBT, Govt. Of West Bengal.

Before joining to Presidency, I served as an Assistant professor in Zoology in Barasat Govt. College for four years. In December 2012, I joined Presidency University in the same post. My major teaching areas are basic animal science, animal physiology, developmental biology, advanced genetics and molecular biology. 

At present, research work in my lab is focused on  

The effect of heavy metals on pregnancy-related complications and neonatal outcomes;  Molecular pathogenesis of malignancy of urological system; Impact of hyperglycemia on molecular carcinogenesis; Identification of susceptible genetic variants for the pathogenesis of atopic conditions including asthma.

Graduate and Postgraduate students are also doing dissertation work under my supervision. 

Life time member of Indian Association for Cancer Research (IACR)

Publication in peer-reviewed journals (After joining Presidency)

1. Ghosh PK, Ghosh A* (2024). Dysregulation of noncoding RNA in chordoma; implications in identifying potential targets for novel therapeutic approaches. Mol Biol Rep 51, 125. https://doi.org/10.1007/s11033-023-09017-9. (IF:2.74)

2. Banerjee A, Bardhan A, Sarkar P, Datta C, Pal DK, Saha A, Ghosh A* (2023). Dysregulation of DNA epigenetic modulators during prostate carcinogenesis in an eastern Indian patient population; prognostic implications. Pathology-Research and Practice, 154970. https://doi.org/10.1016/j.prp. 2023.54970. (IF: 2.8)

3. Bardhan A, Banerjee A, Pal DK, Ghosh A* (2023). HAGLR, A Long Non-coding RNA of Potential Tumor Suppressive Function in Clear Cell Renal Cell Carcinoma: Diagnostic and Prognostic Implications. Mol Biotechnol (2023). https://doi.org/10.1007/s12033-023-00948-z. IF:2.8

4. Basu J, Mukherjee R, Sahu P, Datta C, Chowdhury S, Mandal D, Ghosh A* (2023). Association of common variants of TCF7L2 and PCSK2 with gestational diabetes mellitus in West Bengal, India. Nucleosides Nucleotides Nucleic Acids.1-18. doi: 10.1080/15257770.2023.2248201. IF: 1.5

5. Dalal S, Adhikary J, Roy A, Biswas SS, Mukhopadhaya PK, Acharya S, Ghosh A* (2022). lmpact of hyperglycemia on the expression of GLUT1 during oral carcinogenesis in rats. Molecular Biology Reports. https://doi.org/10.1007/s11033-022-07653-1. IF: 2.74

6. Sarkar P, Malik S, Banerjee A, Datta C, Pal DK, Ghosh A, Saha A (2022). Differential Microbial Signature Associated with Benign Prostatic Hyperplasia and Prostate Cancer. Frontiers in Cellular and Infection Microbiology (Accepted). Journal: Frontiers in Cellular and Infection Microbiology. http://doi: 10.3389/fcimb.2022.894777. IF: 6.07.

7. Bardhan A, Banerjee A, Basu K, Pal DK, Ghosh A* (2022). PRNCR1: a long non-coding RNA with a pivotal oncogenic role in cancer. Hum Genet 41(1):15-29. IF: 5.88

8. Basu M, Chatterjee A, Chakraborty B, Chatterjee E, Ghosh S, Samadder S, Pal DK, Roy A, Chakrabarti J, Ghosh A, Panda CK (2021). High nuclear expression of HIF1α, synergizing with inactivation of LIMD1 and VHL, portray worst prognosis among the bladder cancer patients: association with arsenic prevalence. J Cancer Res Clin Oncol.  doi: 10.1007/s00432-021-03661-z. PMID: 34080067. IF: 4.32

9. Ghosh S, Basu M, Banerjee K, Chaudhury SP, Paul T, Bera DK, Pal DK, Sk UH, Panda CK, Ghosh A*. (2021). Arsenic level in bladder tumor of patients from an exposed population: association with progression and prognosis. Future Oncol.  doi: 10.2217/fon-2020-0154. Epub ahead of print. PMID: 33648348. IF:3.67

10. Basu M, Chakraborty B, Ghosh S, Samadder S, Dutta S, Roy A,  Pal DK, Ghosh A, Panda CK (2021). Divergent molecular profile of PIK3CA gene in arsenic associated bladder carcinoma. Mutagenesis;  https://doi.org/10.1093/mutage/geaa031. IF:2.95

11. Laha A, Ghosh A, Moitra S, Biswas H, Saha NC, Bhattacharya S, Saha GK, Podder S (2020). Association of HLA-DQ and IL13 gene variants with challenge-proven shrimp allergy in West Bengal, India. Immunogenetics. doi: 10.1007/s00251-020-01185-3. IF: 3.33

12. Pal DK, Agrawal A, Ghosh S, Ghosh A (2020). Association of arsenic with recurrence of urinary bladder cancer. Trop Doct.;50(4):325-330. doi: 10.1177/0049475520930155. IF: 0.82

13. Jain P, Ghosh A, Jana D, Pal DK (2020). Chronic pelvic pain syndrome/chronic prostatitis: Is it related to human papillomavirus infection? A case-control study from Eastern India. Urologia ;87(3):137-141. doi: 10.1177/0391560319899848

14. Basu M, Ghosh S, Roychowdhury S, Samadder S, Das P, Addya S, Roy A,  Pal DK, Roychoudhury S, Ghosh A, Panda CK (2020). Integrative genomics and pathway analysis identified prevalent FA-BRCA pathway alterations in arsenic-associated urinary bladder carcinoma: Chronic arsenic accumulation in cancer tissues hampers the FA-BRCA pathway. Genomics;112 (6):5055-5065. IF:4.31

15. Laha A, Ghosh A, Moitra S, Saha I, Kumar Saha G, Bhattacharya S, Podder S (2019).  Association of the STAT6 rs3024974 (C/T) Polymorphism with IgE-Mediated  Food  Sensitization among West  Bengal Population in India. Int Arch Allergy Immunol. doi: 10.1159/000504575. [Epub ahead of print]. IF:3.76

16. Adhikary J, Chakraborty S, Dalal S, Basu S, Dey A, Ghosh A* (2019) Circular PVT1: an oncogenic non-coding RNA with emerging clinical importance. J Clin Pathol. jclinpath-2019-205891. doi: 10.1136/jclinpath-2019-205891. [REVIEW, Epub ahead of print]. IF: 4.46.

17. Basu J, Datta C,  Chowdhury S,  Mandal D, Mondal NK,  Ghosh A* (2018). Gestational Diabetes Mellitus in a Tertiary Care Hospital of Kolkata, India: Prevalence, Pathogenesis and Potential Disease Biomarkers. Experimental and Clinical Endocrinology & Diabetes. DOI: 10.1055/a-0794-6057. IF: 2.42.

18. Ghosh A*, Dutta S, Podder S*, Mondal P, Laha A, Saha NC, Moitra S, Saha  GK (2018).  Sensitivity to House Dust Mites Allergens with Atopic Asthma and Its Relationship with CD14 C(-159T) Polymorphism in Patients of West Bengal, India. J Med Entomol. 10;55(1):14-19. doi: 10.1093/jme/tjx178. IF: 2.43.

19. SGK Dutta S, Mondal P, Saha NC, Moitra S , Podder S*, Ghosh A* (2017). Role of offending out-door aero-allergen and CD14 C(-159)T polymorphism in development and severity of asthma in a Kolkata patient population. African Health Sciences, 17 (Issue 4), 1101-1109. IF:1.10.

20. Maiti GP, Ghosh A, Mondal P, Baral A, Datta S, Samadder S, Nayak SP, Chakraborty J, Biswas J, Sikder N, Chowdhury S, Roy B, Roychowdhury S, Panda CK. The SNP rs1049430 in the 3'-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications in head and neck squamous cell carcinoma. Biochim Biophys Acta. (2015) Feb 26. pii: S0925-4439(15)00060-5. doi: 13.1016/j.bbadis.2015.02.009. [Epub ahead of print]. IF: 6.33.

21. Maiti GP, Ghosh A, Mondal P, Ghosh S, Chakraborty J, Roy A, Roychowdhury S, Panda CK. (2015) Frequent inactivation of SLIT2 and ROBO1 signaling in head and neck lesions: clinical and prognostic implications. Oral Surg Oral Med Oral Pathol Oral Radiol.  Feb;119(2):202-12. doi: 10.1016/j.oooo.2014.09.029. Epub 2014 Oct 2. IF: 2.53

22. Maity GP, Mondal P, Mukherjee N, Ghosh A, Chakraborty J., Roychoudhury S. and Panda C. K. (2013) Overexpression of EGFR in head and neck squamous cell carcinoma is associated with inactivation of SH3GL2 and CDC25A genes. PLoS ONE; https://doi.org/10.1371/journal. pone. 0063440. IF:3.75.

23. Ghosh A, Maiti GP, Bandopadhyay MN, Chakraborty J, Biswas J, Roychoudhury S, Panda CK  (2013). Inactivation of 9q22.3 Tumor Suppressor Genes Predict Outcome for Patients with Head and Neck Squamous Cell Carcinoma. Anticancer Res. Mar;33(3):1215-1220.  IF: 2.48.                                                                                                                                                                                                                                                                                                           *Correspondence

Book Chapters (After joining Presidency)

1. Das S, Ghosh A.* (2024). Small Molecule Therapeutics Targeting Ligand-Independent Activation of Androgen Receptor in Prostate Cancer. In: Pathak, S., Banerjee, A., Duttaroy, A.K. (eds) Small Molecules for Cancer Treatment. Springer, Singapore. https://doi.org/10.1007/978-981-96-0301-5_1. 

2. Chatterjee M, Ghosh A* (2023). Dysregulation of phospholipase C signaling pathway in breast and colorectal cancer: Association with progression and prognosis. Phospholipases in Physiology and Pathology, 2: 109-123. Academic Press (AP), An imprint of Elsevier.  https:// doi. org/10.1016/B978-0-323-95696-3.00004-1. 

3. Chatterjee M, Ghosh P, Ghosh A* (2022). (Book Chapter). Animal models for prostate cancer research; a mechanistic outlook on the challenges and recent progress. Handbook of Animal Models and its Uses in Cancer Research , Springer, Singapore. https://doi.org/10.1007/978-981-19-1282-5_20-1.

4. Bardhan A., Ghosh A* (2022). (Book Chapter). Oxidative Stress Associated Non-coding RNAs in Pathogenesis of Urologic Cancers; Prognostic and Therapeutic Importance. In: Chakraborti S. (eds) Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Springer, Singapore. https://doi.org/10.1007/978-981-16-1247-3_236-1.

*Correspondence